webinar cell counting and viability automation

Vi-CELL BLU Cell Viability Analyzer

The faster Vi-CELL BLU automates the Trypan Blue Dye Exclusion method for cell viability analysis. The Vi-CELL BLU expedites processing by now having the option to use a 24-position sample carousel or a 96 well plate for sample delivery.

Additional enhancements incorporated in the Vi-CELL BLU include:

Fully automated sample preparation, analysis and post-run cleaning
Small sample size
Fast sample processing time
Small laboratory footprint
Flexible sample introduction – carousel or 96 well plate
User-friendly reagent system
Cell viability reported in percentage, concentration, and cell count
Large sample capacity
Data integrity tools

Watch how the Vi-CELL BLU works - Visit our video gallery

Vi-CELL BLU Cell Viability Analyzer Features

Increased Productivity

FAST mode
24-position carousel
Supports 96 well plate sample introduction
Customizable analysis parameters

Flexibility and Ease of Use

Easy sample vial dispensing
Easy load reagent pak
Load on the go processing
Clean room kit option

Reagent Pack

RFID Tracking of reagent part number, lot number, activities, and expiration date
Easy load for automated sample prep
Reagent pack complete with Trypan Blue dye, buffer, disinfectant and cleaning solutions

Data Integrity and Compliance

Audit trail
Error log files
Electronic signature capability
Secure user sign-on
User level permissions
Administrative configuration tools
IQ/OQ

Introducing the Vi-CELL BLU

Vi-CELL BLU Cell Viability Analyzer Specifications

Item Specifications Referenced

C23660

Documentation

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Title	Description
Vi-CELL BLU vs. Vi-CELL XR: Comparison of System Specifications
Vi-CELL BLU Cell Viability Analyzer Software
Cell Type Guidelines & Optimization
Mastering Cell Counting {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Cell line development is a highly-involved, multi-week workflow that involves the plating, screening, and expansion of single cell-derived clones to establish a protein-expression cell line. This complex process required significant throughput of sterile cell manipulations, long-term incubations, centrifugation, cell counting, monoclonality determination and growth tracking, and protein production assessment.
Cellular Challenges: Taking an Aim at Cancer {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Immunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy, the result is an expanded population of T cells primed to recognize and eradicate malignant tumor cells that would otherwise escape immune detection.
Vi CELL BLU FAST Mode Option {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This paper explains the optional FAST Mode of operation in the Vi-CELL BLU cell viability analyzer which can be used in either plate or carousel configuration to significantly reduce sample to sample operation times.
Cell Counting Performance of Vi–Cell BLU Cell Viability Analyzer {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	To determine the cell counting performance of the Vi–CELL BLU we adapted the protocol outline by NIST to determine the performance of the new Vi–Cell BLU Cell Viability Analyzer.
Vi-CELL BLU Regulatory Compliance - 21 CFR Part 11 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	The following information describes the relevant portions of the 21 CFR Part 11 regulations and their implementation using the Vi-CELL BLU control software.
Vaporized Hydrogen Peroxide Decontamination of Vi–CELL BLU Instrument {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note demonstrates the method and results for testing the Vi-CELL BLU for VHP resistance.
Method for Determining Cell Type Parameter Adjustment to Match Legacy Vi CELL XR {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note details how you can use the plate loader feature on the Vi-CELL BLU to match cell types to give cell counts and viability levels equivalent to those obtained on existing Vi-CELL XR instruments.
Matching Cell Counts between Vi–CELL XR and Vi–CELL BLU {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This paper demonstrates a series of different cell types run on the Vi-CELL XR and duplicate samples run on the Vi-CELL BLU. The cells were then reanalyzed adjusting the cell type parameters until a new cell type was generated that gave cell concentrations within +/–5% and viable cell density levels within +/–2.5% of the Vi-CELL XR.
Specification Comparison of Vi–CELL XR and Vi–CELL BLU {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	The Vi–CELL BLU leverages the key performance features of the Vi–CELL XR but incorporates many design improvements that our customers have requested over the years. This paper highlights the differences in specifications between the two instruments.
Considerations of Cell Counting Analysis when using Different Types of Cells {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This paper reviews several different cell types and cell preparation approaches using standard cells, such as, CHO cells, EL4 cells, SF9 cells, and HELA cell cultures.
Evaluation of Instrument to Instrument Performance of the Vi-CELL BLU Cell Viability Analyzer {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note details one of the key strengths of the Vi–CELL BLU, the ability to fine tune the performance to minimize variability between different instruments. This is particularly valuable in facilities that utilize multiple instruments but can also be important when instruments are occasionally shared between departments.
Bioprocessing Cell Culture	Within bioprocessing there are two QC processes. One is Production QC where technicians ensure the cells are growing and their media fits within specified ranges for cell growth. The other is Product Efficacy QC, where assays are run to test the efficacy of the drug prior to distribution.
Maintaining Data Integrity: Understanding FDA ALCOA Guidance	21 CFR part 11 ALCOA defines good data integrity practice as creating records that are attributable to the technician carrying out the testing, are legible, are created contemporaneously, original and accurate.
Vi-CELL BLU Customer Training {C4C1CD4C-C652-4308-97B2-70CEE33E48FF}	eLearning (50 minutes): This curriculum contains 4 online courses to help you operate your new Vi-CELL BLU. Purchase of this curriculum gives you access for 1 year. You can complete and retake each course whenever you need it
21 CFR Part 11 Compliance with the Vi-CELL BLU Cell Viability Analyzer
Dekontamination des Vi-CELL BLU Geräts mit verdampftem Wasserstoffperoxid {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	In vielen Laboren ist eine Dekontamination des gesamten Geräts gewünscht und im Fall des Umgangs mit
Vaporized Hydrogen Peroxide Decontamination of Vi-CELL BLU Instrument {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note demonstrates the method and results for testing the Vi-CELL BLU for VHP resistance.
Matching Cell Counts between Vi-CELL XR and Vi-CELL BLU {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note explains the flexibility to adjust the cell type settings to match results obtained from an equivalent sample when run on the Vi-CELL XR on the Vi-CELL BLU.
Evaluation of Instrument to Instrument Performance of the Vi-CELL BLU Cell Viability Analyzer {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note examines the comparability of results from multiple Vi-CELL BLU cell viability analyzers.
Vi-CELL BLU Regulatory Compliance - 21 CFR Part 11	The following document describes the relevant portions of the 21 CFR Part 11 regulations and their implementation using the Vi-CELL BLU control software.
Vi-CELL BLU Cell Viability Analyzer Brochure {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	Product brochure for the New VI-CELL BLU Cell Viability Analyzer. See what BLU can do for you
ALCOA+ Infographic	Guidance on Maintaining Data Integrity Infographic
Manufacturing Processes for Engineered T-Cell Therapy – CAR-T	Brochure presenting the CAR-T cell therapy workflow and associated product portfolio
Vi-CELL BLU FAST Mode Option {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note explains the optional FAST Mode of operation in the new Vi-CELL BLU which can be used in either plate or carousel configuration to significantly reduce sample to sample operation times.
Method for Determining Cell Type Parameter Adjustment to Match Legacy Vi-CELL XR {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note assists in matching Vi-CELL BLU cell types to give cell counts and viability levels equivalent to those obtained on existing Vi-CELL XR instruments.
ViCELL BLU and ViCELL XR Specifications	The Vi–CELL BLU leverages the key performance features of the Vi–CELL XR but incorporates many design improvements that our customers have requested over the years. This paper highlights the differences in specifications between the two instruments.
Considerations of Cell Counting Analysis when using Different Types of Cells {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note reviews several different cell types and cell preparation approaches using standard cells.
Bewertung der Leistung des Vi–CELL BLU Zellvitalitäts analysator bei der Nutzung mehrerer Geräte {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Beckman Coulter Life Sciences freut sich, Ihnen den neuen Vi–CELL BLU Zellvitalitätsanalysator vorzustellen
Quality Control Testing Instrumentation Solutions for GMP Manufacturing Brochure {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	Brochure on instruments designed for Raw Materials QC, Production QC, and Final Product QC
Vi-CELL BLU Zellanalysator Broschüre {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}
Vi–CELLBLU im Fast Mode {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Vi–CELL BLU mit einem optionalen Betriebsmodus „Schnell“ ausgestattet, der in Platten- wie auch Karussellkonfi gur ationen genutzt werden kann, um den Wechsel von einer Probe zur nächsten erheblich zu beschleunigen
cell-viability-vi-cell-blu-match-cell-counts-xr-blu-201904-german {442DF88C-CA7F-4B78-AF75-9D2B985534C0}
cell-viability-vi-cell-blu-cell-type-analysis-types-201904-german {442DF88C-CA7F-4B78-AF75-9D2B985534C0}
Methode zur Bestimmung der Zelltypparameter Anpassung zum Abgleich mit dem Vi–CELL XR {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Mit der Einführung des neuen Vi–CELL BLU ist es nun möglich, den Plattenmodus für komplexere Versuchsanordnungen zu nutzen.
Cell Counting Performance of Vi-CELL BLU Cell Viability Analyzer	This application note examines how the new Vi-CELL BLU performs within specifications so that any instrument variability can be eliminated from the sample measurement.
21 CFR Part 11 QC Instrument Suite {279C6CA2-9797-4CFE-9CAA-5EAFAC29B60D}	This datasheet outlines QC steps, instruments, applications, regulations, and ALCOA compatibility.
Product Solutions for Viral Research Workflows {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	Brochure: Discover product solutions for sample collection, isolation and preparation, virus identification, antibody analysis, and vaccine and therapy development.
生死細胞オートアナライザー Vi-CELL BLU {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	より速くなったVi-CELL BLUは、トリパンブルー染色法による細胞の生死細胞解析を自動化しています。サンプルの供給に、24-ポジションのサンプルカローセル、もしくは、96ウエルプレートを使用できるようになり、より効率よく測定を行えるようになりました。
アプリケーションノート：過酸化水素ガス滅菌によるVi–CELL BLU の性能評価 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	クリーンルームで機器を使用する場合、機器が除染できることが望まれます。クリーンルームでのVi-CELL BLUの使用を目的とし、過酸化水素ガス滅菌による機器性能への影響を評価を行いました。
アプリケーションノート:Vi–CELL XRとVi–CELL BLUとの仕様比較 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	グローバルスタンダードのセルカウンターVi-CELL XRの優れた機能を継承し開発されたVi-CELL BLUの仕様について、Vi-CELL XRと比較しました。
アプリケーションノート：Vi–CELL BLU 高速モード {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Vi-CELL BLUに搭載されている高速モードは、セルカウントの解析速度を大きく短縮します。様々な濃度のサンプル計測においてもキャリーオーバーはほぼ影響なく、正確にセルカウントが行えます。
アプリケーションノート:生死細胞オートアナライザー Vi–Cell BLU の計数性能評価 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	セルカウンターとしての性能を評価するため、NISTで採用されている方法を用いて細胞の低濃度から高濃度に至る広い濃度範囲を評価しました。Vi-CELL BLUは高い計数性能を有していることを示します。
アプリケーションノート：Vi–CELL XR とVi–CELL BLUの計数マッチング方法 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	新製品Vi-CELL BLUのセルカウントをVi-CELL XRのセルカウントと一致させる方法を紹介します。新技術を搭載したセルカウンターをいかに既存機器の計数に合わせるか詳しく説明します。
アプリケーションノート：Vi-CELL BLUの計数値をVi-CELL XRに素早く一致させるための有効な方法 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Vi-CELL BLUのプレート機能を使うことによって、Vi-CELL XRのセルカウントに素早く一致させる方法を紹介します。
アプリケーションノート：Vi–CELL BLU の機器間差評価テスト {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	セルカウンターをはじめ、あらゆる機器の機器間差が小さいことは、課題の一つです。GMP施設、遠隔共同研究において、Vi-CELL BLUの大きな強みは機器間差が最小限に抑えられるよう設計されています。
アプリケーションノート：96ウェルプレートを利用して細胞の計数条件を決める有効な方法 {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	セルカウントまでの細胞の準備は従来の方法で大丈夫でしょうか。Vi-CELL BLUのプレート機能を使うことで様々な細胞の新たな特徴が見えてきます。

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Vi-CELL BLU Cell Viability Analyzer

Choose a Vi Cell BLU Model

Vi-CELL BLU Cell Viability Analyzer Features

Increased Productivity

Flexibility and Ease of Use

Reagent Pack

Data Integrity and Compliance

Introducing the Vi-CELL BLU

Vi-CELL BLU Cell Viability Analyzer Specifications

Vi-CELL BLU Cell Viability Analyzer

Request Quote

Cell Type Guidelines

Features

21 CFR Part 11

Videos

Software

Reagents

Tech Docs

Choose a Vi Cell BLU Model

Vi-CELL BLU Cell Viability Analyzer Features

Increased Productivity

Flexibility and Ease of Use

Reagent Pack

Data Integrity and Compliance

Introducing the Vi-CELL BLU

Vi-CELL BLU Cell Viability Analyzer Specifications

Documentation

Technical Documents

Related Parts

Vi-CELL BLU Reagent Kit

Vi-CELL BLU Quad Pak (Qty 4)

Vi-CELL BLU 10.0M Single-Use Concentration Control (25 Vials)

Vi-CELL BLU 4.0M Single-Use Concentration Control (20 Vials)

Vi-CELL BLU 2.0M Single-Use Concentration Control (20 Vials)

Vi-CELL BLU 0.5M Single-Use Concentration Control (20 Vials)